IRIS
AMBROSINO, Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 1.982
AS - Asia 1.193
EU - Europa 1.082
SA - Sud America 258
AF - Africa 36
Continente sconosciuto - Info sul continente non disponibili 14
Totale 4.565
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Nazione #
US - Stati Uniti d'America 1.799
SG - Singapore 444
CN - Cina 432
UA - Ucraina 248
BR - Brasile 207
FR - Francia 201
IT - Italia 156
CA - Canada 146
SE - Svezia 136
DE - Germania 99
GB - Regno Unito 72
KR - Corea 56
FI - Finlandia 55
TR - Turchia 47
HK - Hong Kong 45
IN - India 40
NL - Olanda 40
VN - Vietnam 35
MX - Messico 24
AR - Argentina 18
RU - Federazione Russa 18
JP - Giappone 16
PL - Polonia 15
BD - Bangladesh 14
EU - Europa 14
MA - Marocco 13
IQ - Iraq 11
PK - Pakistan 10
CI - Costa d'Avorio 8
EC - Ecuador 8
VE - Venezuela 7
ES - Italia 6
BE - Belgio 5
CO - Colombia 5
CZ - Repubblica Ceca 5
IL - Israele 5
UZ - Uzbekistan 5
AT - Austria 4
CL - Cile 4
RO - Romania 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
BO - Bolivia 3
ID - Indonesia 3
KG - Kirghizistan 3
LT - Lituania 3
NI - Nicaragua 3
NP - Nepal 3
PH - Filippine 3
SA - Arabia Saudita 3
TN - Tunisia 3
AZ - Azerbaigian 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
EE - Estonia 2
EG - Egitto 2
IE - Irlanda 2
JO - Giordania 2
KE - Kenya 2
KZ - Kazakistan 2
LB - Libano 2
MY - Malesia 2
PA - Panama 2
PT - Portogallo 2
AL - Albania 1
BH - Bahrain 1
BY - Bielorussia 1
BZ - Belize 1
CD - Congo 1
CR - Costa Rica 1
ET - Etiopia 1
GN - Guinea 1
HN - Honduras 1
IR - Iran 1
JM - Giamaica 1
KW - Kuwait 1
LU - Lussemburgo 1
LV - Lettonia 1
ME - Montenegro 1
MT - Malta 1
PE - Perù 1
PR - Porto Rico 1
PY - Paraguay 1
QA - Qatar 1
RS - Serbia 1
TH - Thailandia 1
VG - Isole Vergini Britanniche 1
YT - Mayotte 1
ZA - Sudafrica 1
ZW - Zimbabwe 1
Totale 4.565
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Città #
Jacksonville 204
Dallas 194
San Jose 167
The Dalles 148
Toronto 132
Ashburn 128
Chandler 126
Singapore 110
Boardman 82
Seoul 56
Beijing 55
Helsinki 53
Strasbourg 48
Princeton 45
Hong Kong 44
Nanjing 42
Wilmington 42
London 30
Dearborn 29
Istanbul 29
Milan 28
Meppel 26
Napoli 24
Los Angeles 22
Chicago 21
Ogden 21
Shenyang 19
Mexico City 18
Falkenstein 17
Guangzhou 17
Munich 17
Shanghai 16
Jinan 14
Ningbo 14
Orem 14
São Paulo 14
Jiaxing 13
Tianjin 13
Brooklyn 12
Frankfurt am Main 12
Ho Chi Minh City 12
Changsha 11
New York 11
Santa Clara 11
Seattle 11
Tokyo 11
Zhengzhou 11
Ankara 10
Ann Arbor 10
Nanchang 10
Warsaw 10
Boydton 9
Chennai 9
Düsseldorf 9
Hangzhou 9
Hanoi 9
Abidjan 8
Assago 8
Hebei 8
Amsterdam 7
Atlanta 7
Belo Horizonte 7
Bremen 7
Manchester 7
Naples 7
Rio de Janeiro 7
Stockholm 7
Xi'an 7
Barnet 6
Columbus 6
Montreal 6
Norwalk 6
Redwood City 6
Taizhou 6
Angri 5
Council Bluffs 5
Haiphong 5
Porto Alegre 5
Pune 5
Quito 5
San Francisco 5
Shenzhen 5
Boston 4
Brno 4
Brussels 4
Buffalo 4
Cagliari 4
Delhi 4
Gunzenhausen 4
Kensington 4
Krakow 4
Lahore 4
Mumbai 4
Ottawa 4
Rome 4
Secaucus 4
Tashkent 4
Trieste 4
Washington 4
Baghdad 3
Totale 2.513
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Nome #
Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons 148
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 133
Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain 120
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide 118
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy 114
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 110
Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin 108
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 107
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 105
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 105
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 105
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 104
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors 103
COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study 102
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 100
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy 99
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels 99
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 98
Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features 94
Neurounina-1, a novel compound that increases Na+/Ca 2+ exchanger activity, effectively protects against stroke damage 89
Comparative Safety of Originator and Biosimilar Epoetin Alfa Drugs: An Observational Prospective Multicenter Study 85
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin 85
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes 82
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 81
The ever changing moods of calmodulin: How structural plasticity entails transductional adaptability 81
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels 81
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia 80
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 79
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 79
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin 79
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months 79
De novo variants in KCNA3 cause developmental and epileptic encephalopathy 77
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy 76
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 75
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4- chloro-benzyl)amino]-N-[[(2,4-dimethylbenzyl)-amino]iminomethyl] -pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca 2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 75
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 74
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 74
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology 74
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 72
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 72
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine 72
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 71
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes 69
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP 2 -Dependent K + Channel Gating 69
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists 69
Pharmacological targeting of neuronal Kv7.2/3 channels: A focus on chemotypes and receptor sites 69
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel 67
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 66
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 65
KCNT2-related disorders: phenotypes, functional and pharmacological properties 62
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy 60
Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study 56
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 56
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 52
Pharmacological approaches in drug-resistant pediatric epilepsies caused by pathogenic variants in potassium channel genes 37
Totale 4.661
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Categoria #
all - tutte 28.800
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.800
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021109 0 0 0 0 0 0 0 0 0 53 50 6
2021/2022281 7 8 133 30 0 5 3 48 16 3 3 25
2022/2023558 132 24 3 44 30 106 1 47 107 9 36 19
2023/2024238 38 36 16 9 9 10 10 0 53 12 18 27
2024/20251.020 69 15 39 30 99 82 106 82 128 178 123 69
2025/20261.561 122 180 264 105 130 82 253 96 125 204 0 0
Totale 4.661