IRIS
AMBROSINO, Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 1.055
EU - Europa 807
AS - Asia 341
Continente sconosciuto - Info sul continente non disponibili 14
AF - Africa 7
SA - Sud America 2
Totale 2.226
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Nazione #
US - Stati Uniti d'America 924
CN - Cina 275
UA - Ucraina 246
FR - Francia 182
SE - Svezia 132
CA - Canada 131
IT - Italia 86
DE - Germania 46
FI - Finlandia 40
GB - Regno Unito 32
NL - Olanda 28
TR - Turchia 28
SG - Singapore 15
EU - Europa 14
IN - India 10
CI - Costa d'Avorio 7
JP - Giappone 5
CZ - Repubblica Ceca 4
AT - Austria 2
BE - Belgio 2
BR - Brasile 2
CH - Svizzera 2
IL - Israele 2
PK - Pakistan 2
AE - Emirati Arabi Uniti 1
ES - Italia 1
ID - Indonesia 1
IR - Iran 1
MT - Malta 1
PT - Portogallo 1
QA - Qatar 1
RO - Romania 1
RU - Federazione Russa 1
Totale 2.226
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Città #
Jacksonville 203
Chandler 126
Toronto 126
Boardman 82
Strasbourg 48
Princeton 45
Wilmington 42
Helsinki 40
Nanjing 40
Dearborn 29
Istanbul 27
London 26
Meppel 26
Napoli 24
Ogden 21
Shenyang 18
Chicago 16
Guangzhou 15
Shanghai 15
Ningbo 14
Jiaxing 13
Jinan 13
Beijing 11
Changsha 11
Zhengzhou 11
Ann Arbor 10
Nanchang 10
Boydton 9
Milan 9
Tianjin 9
Hebei 8
Abidjan 7
Bremen 7
Norwalk 6
Redwood City 6
Taizhou 6
Hangzhou 5
Los Angeles 5
Naples 5
Brno 4
Gunzenhausen 4
Pune 4
Shenzhen 4
Xi'an 4
Frankfurt am Main 3
Introdacqua 3
North Charleston 3
Orange 3
Pomigliano D'arco 3
Portland 3
Redmond 3
Rui'an 3
Saint-maur-des-fossés 3
Santa Clara 3
Stockholm 3
Wuhan 3
Amsterdam 2
Ancona 2
Ashburn 2
Benevento 2
Bisaccia 2
Brooklyn 2
Brussels 2
Bryn Mawr 2
Buffalo 2
Campobasso 2
Chessel 2
Dallas 2
Molise 2
Montfermeil 2
Montréal 2
New York 2
Nuremberg 2
Ottawa 2
Pagani 2
Petah Tikva 2
Quanzhou 2
Rome 2
Secaucus 2
Singapore 2
Tokyo 2
Verona 2
Vienna 2
Washington 2
Wuxi 2
Zibo 2
Agropoli 1
Alatri 1
Ankara 1
Avezzano 1
Bangor 1
Beccles 1
Canosa Di Puglia 1
Castellammare di Stabia 1
Doha 1
Dongyang 1
Ferentino 1
Genova 1
Imsida 1
Jakarta 1
Totale 1.274
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Nome #
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 81
Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain 71
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 68
Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons 68
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 65
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide 64
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 62
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy 61
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 57
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy 56
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 55
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 55
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 55
Neurounina-1, a novel compound that increases Na+/Ca 2+ exchanger activity, effectively protects against stroke damage 54
Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin 53
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 52
Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features 51
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors 51
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin 50
The ever changing moods of calmodulin: How structural plasticity entails transductional adaptability 50
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels 50
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia 49
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels 48
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin 48
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 46
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 43
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 43
Pharmacological targeting of neuronal Kv7.2/3 channels: A focus on chemotypes and receptor sites 43
Comparative Safety of Originator and Biosimilar Epoetin Alfa Drugs: An Observational Prospective Multicenter Study 41
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 41
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4- chloro-benzyl)amino]-N-[[(2,4-dimethylbenzyl)-amino]iminomethyl] -pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca 2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 41
COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study 40
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists 40
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology 40
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes 39
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 39
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 39
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy 38
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 37
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 37
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP 2 -Dependent K + Channel Gating 37
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 35
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 34
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 30
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes 27
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months 27
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 23
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine 22
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 15
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel 15
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy 10
KCNT2-related disorders: phenotypes, functional and pharmacological properties 8
De novo variants in KCNA3 cause developmental and epileptic encephalopathy 7
Totale 2.311
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Categoria #
all - tutte 16.411
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.411
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020223 0 0 0 0 3 77 21 72 1 44 3 2
2020/2021468 43 40 16 44 12 107 2 44 51 53 50 6
2021/2022281 7 8 133 30 0 5 3 48 16 3 3 25
2022/2023558 132 24 3 44 30 106 1 47 107 9 36 19
2023/2024238 38 36 16 9 9 10 10 0 53 12 18 27
2024/2025231 69 15 39 30 78 0 0 0 0 0 0 0
Totale 2.311