IRIS
AMBROSINO, Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 1.294
EU - Europa 924
AS - Asia 537
SA - Sud America 166
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 14
Totale 2.949
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Nazione #
US - Stati Uniti d'America 1.151
CN - Cina 293
UA - Ucraina 246
FR - Francia 195
BR - Brasile 152
SG - Singapore 139
CA - Canada 135
SE - Svezia 133
IT - Italia 113
DE - Germania 75
FI - Finlandia 49
GB - Regno Unito 37
NL - Olanda 36
TR - Turchia 35
HK - Hong Kong 20
EU - Europa 14
RU - Federazione Russa 14
IN - India 12
CI - Costa d'Avorio 7
JP - Giappone 6
PK - Pakistan 6
AR - Argentina 5
CZ - Repubblica Ceca 5
MX - Messico 5
AT - Austria 4
IL - Israele 4
BE - Belgio 3
BO - Bolivia 3
EC - Ecuador 3
IQ - Iraq 3
KG - Kirghizistan 3
MA - Marocco 3
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
EE - Estonia 2
IE - Irlanda 2
KZ - Kazakistan 2
PT - Portogallo 2
TN - Tunisia 2
UZ - Uzbekistan 2
VE - Venezuela 2
AL - Albania 1
AZ - Azerbaigian 1
BD - Bangladesh 1
BH - Bahrain 1
EG - Egitto 1
ES - Italia 1
ID - Indonesia 1
IR - Iran 1
JM - Giamaica 1
JO - Giordania 1
KE - Kenya 1
LU - Lussemburgo 1
LV - Lettonia 1
MT - Malta 1
NI - Nicaragua 1
NP - Nepal 1
PA - Panama 1
QA - Qatar 1
RO - Romania 1
TH - Thailandia 1
UY - Uruguay 1
VN - Vietnam 1
Totale 2.949
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Città #
Jacksonville 203
Chandler 126
Toronto 126
The Dalles 116
Boardman 82
Strasbourg 48
Helsinki 47
Princeton 45
Wilmington 42
Nanjing 41
Singapore 37
Dearborn 29
London 28
Istanbul 27
Meppel 26
Napoli 24
Ogden 21
Hong Kong 19
Shenyang 19
Falkenstein 17
Chicago 16
Guangzhou 16
Milan 15
Shanghai 15
Jinan 14
Ningbo 14
Jiaxing 13
Los Angeles 12
São Paulo 12
Beijing 11
Changsha 11
Seattle 11
Zhengzhou 11
Ann Arbor 10
Nanchang 10
Boydton 9
Düsseldorf 9
Tianjin 9
Hebei 8
Abidjan 7
Bremen 7
Amsterdam 6
Assago 6
Belo Horizonte 6
Brooklyn 6
Norwalk 6
Redwood City 6
Rio de Janeiro 6
Santa Clara 6
Taizhou 6
Xi'an 6
Angri 5
Ashburn 5
Frankfurt am Main 5
Hangzhou 5
Mexico City 5
Naples 5
Pune 5
Ankara 4
Atlanta 4
Brno 4
Cagliari 4
Gunzenhausen 4
Ottawa 4
Shenzhen 4
Stockholm 4
Bishkek 3
Brussels 3
Introdacqua 3
La Paz 3
Lauterbourg 3
North Charleston 3
Orange 3
Pomigliano D'arco 3
Portland 3
Porto Alegre 3
Redmond 3
Rui'an 3
Saint-maur-des-fossés 3
Secaucus 3
Shijiazhuang 3
Tokyo 3
Wuhan 3
Ancona 2
Baghdad 2
Belford Roxo 2
Benevento 2
Bisaccia 2
Bryn Mawr 2
Buffalo 2
Campobasso 2
Chessel 2
Curitiba 2
Dallas 2
Dourados 2
Dublin 2
Goiânia 2
Lahore 2
Manaus 2
Molise 2
Totale 1.575
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Nome #
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 103
Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons 89
Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain 86
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide 82
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy 76
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 75
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 74
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 74
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 73
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 73
Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin 72
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 72
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy 70
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors 69
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 67
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 67
COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study 65
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels 65
Neurounina-1, a novel compound that increases Na+/Ca 2+ exchanger activity, effectively protects against stroke damage 64
Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features 61
The ever changing moods of calmodulin: How structural plasticity entails transductional adaptability 60
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels 60
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin 59
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin 57
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes 56
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 56
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia 56
Comparative Safety of Originator and Biosimilar Epoetin Alfa Drugs: An Observational Prospective Multicenter Study 54
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 53
Pharmacological targeting of neuronal Kv7.2/3 channels: A focus on chemotypes and receptor sites 53
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4- chloro-benzyl)amino]-N-[[(2,4-dimethylbenzyl)-amino]iminomethyl] -pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca 2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 51
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 50
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 50
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 48
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 47
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP 2 -Dependent K + Channel Gating 47
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology 47
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy 47
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists 46
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine 46
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 45
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes 45
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 45
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 45
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 43
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 43
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months 43
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 38
KCNT2-related disorders: phenotypes, functional and pharmacological properties 31
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel 30
De novo variants in KCNA3 cause developmental and epileptic encephalopathy 29
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 29
Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study 24
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy 24
Pharmacological approaches in drug-resistant pediatric epilepsies caused by pathogenic variants in potassium channel genes 11
Totale 3.045
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Categoria #
all - tutte 20.513
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.513
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202 0 0 0 0 0 0 0 0 0 0 0 2
2020/2021468 43 40 16 44 12 107 2 44 51 53 50 6
2021/2022281 7 8 133 30 0 5 3 48 16 3 3 25
2022/2023558 132 24 3 44 30 106 1 47 107 9 36 19
2023/2024238 38 36 16 9 9 10 10 0 53 12 18 27
2024/2025965 69 15 39 30 99 82 106 82 128 178 123 14
Totale 3.045