IRIS
AMBROSINO, Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 2.048
AS - Asia 1.297
EU - Europa 1.088
SA - Sud America 258
AF - Africa 36
Continente sconosciuto - Info sul continente non disponibili 14
Totale 4.741
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Nazione #
US - Stati Uniti d'America 1.858
CN - Cina 484
SG - Singapore 475
UA - Ucraina 248
BR - Brasile 207
FR - Francia 201
IT - Italia 161
CA - Canada 148
SE - Svezia 136
DE - Germania 99
GB - Regno Unito 73
KR - Corea 58
FI - Finlandia 55
HK - Hong Kong 51
TR - Turchia 47
IN - India 40
NL - Olanda 40
VN - Vietnam 35
MX - Messico 27
AR - Argentina 18
RU - Federazione Russa 18
JP - Giappone 17
BD - Bangladesh 15
PL - Polonia 15
EU - Europa 14
MA - Marocco 13
IQ - Iraq 11
PK - Pakistan 10
CI - Costa d'Avorio 8
EC - Ecuador 8
MY - Malesia 8
VE - Venezuela 7
ES - Italia 6
AE - Emirati Arabi Uniti 5
BE - Belgio 5
CO - Colombia 5
CZ - Repubblica Ceca 5
ID - Indonesia 5
IL - Israele 5
UZ - Uzbekistan 5
AT - Austria 4
CL - Cile 4
NI - Nicaragua 4
RO - Romania 4
UY - Uruguay 4
BO - Bolivia 3
KG - Kirghizistan 3
LT - Lituania 3
NP - Nepal 3
PH - Filippine 3
SA - Arabia Saudita 3
TN - Tunisia 3
AZ - Azerbaigian 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
EE - Estonia 2
EG - Egitto 2
IE - Irlanda 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
KZ - Kazakistan 2
LB - Libano 2
PA - Panama 2
PT - Portogallo 2
AL - Albania 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
BZ - Belize 1
CD - Congo 1
CR - Costa Rica 1
ET - Etiopia 1
GN - Guinea 1
HN - Honduras 1
IR - Iran 1
KW - Kuwait 1
LU - Lussemburgo 1
LV - Lettonia 1
ME - Montenegro 1
MT - Malta 1
PE - Perù 1
PR - Porto Rico 1
PY - Paraguay 1
QA - Qatar 1
RS - Serbia 1
TH - Thailandia 1
VG - Isole Vergini Britanniche 1
YT - Mayotte 1
ZA - Sudafrica 1
ZW - Zimbabwe 1
Totale 4.741
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Città #
San Jose 205
Jacksonville 204
Dallas 195
The Dalles 148
Toronto 132
Ashburn 130
Chandler 126
Singapore 113
Boardman 82
Beijing 60
Seoul 56
Helsinki 53
Hong Kong 50
Strasbourg 48
Princeton 45
Nanjing 42
Wilmington 42
London 30
Dearborn 29
Istanbul 29
Milan 28
Meppel 26
Napoli 24
Chicago 22
Los Angeles 22
Mexico City 21
Ogden 21
Shenyang 19
Falkenstein 17
Guangzhou 17
Munich 17
Santa Clara 17
Shanghai 16
Tianjin 16
Jinan 14
Ningbo 14
Orem 14
São Paulo 14
Jiaxing 13
Brooklyn 12
Frankfurt am Main 12
Ho Chi Minh City 12
Changsha 11
Nanchang 11
New York 11
Seattle 11
Tokyo 11
Zhengzhou 11
Ankara 10
Ann Arbor 10
Hangzhou 10
Warsaw 10
Boydton 9
Chennai 9
Düsseldorf 9
Hanoi 9
Abidjan 8
Assago 8
Columbus 8
Hebei 8
Amsterdam 7
Atlanta 7
Belo Horizonte 7
Bremen 7
Manchester 7
Montreal 7
Naples 7
Rio de Janeiro 7
Stockholm 7
Xi'an 7
Barnet 6
Norwalk 6
Redwood City 6
Taizhou 6
Angri 5
Council Bluffs 5
Haiphong 5
Kuala Lumpur 5
Porto Alegre 5
Pune 5
Quito 5
San Francisco 5
Shenzhen 5
Boston 4
Brno 4
Brussels 4
Buffalo 4
Cagliari 4
Charlotte 4
Delhi 4
Gunzenhausen 4
Kensington 4
Krakow 4
Lahore 4
Managua 4
Mumbai 4
Ottawa 4
Rome 4
Secaucus 4
Tashkent 4
Totale 2.588
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Nome #
Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons 151
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 134
Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain 132
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide 130
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 121
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy 120
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 112
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels 111
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 111
Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin 108
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 107
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 107
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 107
COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study 106
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors 104
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 102
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 101
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy 100
Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features 97
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 92
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 90
Neurounina-1, a novel compound that increases Na+/Ca 2+ exchanger activity, effectively protects against stroke damage 90
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin 88
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes 85
Comparative Safety of Originator and Biosimilar Epoetin Alfa Drugs: An Observational Prospective Multicenter Study 85
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 84
The ever changing moods of calmodulin: How structural plasticity entails transductional adaptability 84
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia 83
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels 82
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 81
De novo variants in KCNA3 cause developmental and epileptic encephalopathy 80
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology 80
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months 80
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin 79
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4- chloro-benzyl)amino]-N-[[(2,4-dimethylbenzyl)-amino]iminomethyl] -pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca 2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 77
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy 77
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 76
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 76
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 75
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 74
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 72
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine 72
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists 71
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP 2 -Dependent K + Channel Gating 70
Pharmacological targeting of neuronal Kv7.2/3 channels: A focus on chemotypes and receptor sites 70
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes 69
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel 69
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 68
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 66
KCNT2-related disorders: phenotypes, functional and pharmacological properties 63
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy 62
Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study 59
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 57
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 52
Pharmacological approaches in drug-resistant pediatric epilepsies caused by pathogenic variants in potassium channel genes 38
Totale 4.837
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Categoria #
all - tutte 30.542
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.542
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20216 0 0 0 0 0 0 0 0 0 0 0 6
2021/2022281 7 8 133 30 0 5 3 48 16 3 3 25
2022/2023558 132 24 3 44 30 106 1 47 107 9 36 19
2023/2024238 38 36 16 9 9 10 10 0 53 12 18 27
2024/20251.020 69 15 39 30 99 82 106 82 128 178 123 69
2025/20261.737 122 180 264 105 130 82 253 96 125 252 79 49
Totale 4.837