IRIS
AMBROSINO, Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 964
EU - Europa 763
AS - Asia 203
Continente sconosciuto - Info sul continente non disponibili 14
AF - Africa 7
Totale 1.951
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Nazione #
US - Stati Uniti d'America 834
UA - Ucraina 246
CN - Cina 165
FR - Francia 165
SE - Svezia 132
CA - Canada 130
IT - Italia 72
DE - Germania 43
FI - Finlandia 40
GB - Regno Unito 30
NL - Olanda 26
TR - Turchia 22
EU - Europa 14
IN - India 8
CI - Costa d'Avorio 7
JP - Giappone 5
AT - Austria 2
BE - Belgio 2
AE - Emirati Arabi Uniti 1
ES - Italia 1
IR - Iran 1
MT - Malta 1
PT - Portogallo 1
QA - Qatar 1
RO - Romania 1
RU - Federazione Russa 1
Totale 1.951
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Città #
Jacksonville 203
Chandler 126
Toronto 126
Strasbourg 48
Princeton 45
Wilmington 42
Helsinki 40
Nanjing 39
Dearborn 29
Meppel 26
London 25
Napoli 24
Istanbul 21
Ogden 21
Shenyang 18
Chicago 16
Jinan 13
Ningbo 13
Changsha 11
Zhengzhou 11
Ann Arbor 10
Boardman 10
Nanchang 10
Boydton 9
Jiaxing 9
Hebei 8
Abidjan 7
Bremen 7
Guangzhou 7
Tianjin 7
Norwalk 6
Redwood City 6
Taizhou 6
Beijing 5
Hangzhou 5
Gunzenhausen 4
Los Angeles 4
Introdacqua 3
Naples 3
North Charleston 3
Orange 3
Pomigliano D'arco 3
Portland 3
Redmond 3
Saint-maur-des-fossés 3
Stockholm 3
Ancona 2
Ashburn 2
Benevento 2
Bisaccia 2
Brooklyn 2
Brussels 2
Bryn Mawr 2
Campobasso 2
Frankfurt am Main 2
Milan 2
Molise 2
Montréal 2
New York 2
Ottawa 2
Pagani 2
Pune 2
Rome 2
Tokyo 2
Verona 2
Vienna 2
Washington 2
Agropoli 1
Alatri 1
Ankara 1
Avezzano 1
Beccles 1
Canosa Di Puglia 1
Doha 1
Ferentino 1
Genova 1
Imsida 1
Kunming 1
Manassas 1
Miyamachi 1
Morcone 1
Nocera Inferiore 1
Nuremberg 1
Rockville 1
Sagamihara 1
Secaucus 1
Shanghai 1
St Petersburg 1
Vitoria-Gasteiz 1
Totale 1.108
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Nome #
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 76
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 64
Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain 64
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide 59
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy 57
Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons 57
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 56
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 52
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy 51
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 50
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 50
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 50
Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin 49
Neurounina-1, a novel compound that increases Na+/Ca 2+ exchanger activity, effectively protects against stroke damage 49
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 48
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin 47
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels 47
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia 47
The ever changing moods of calmodulin: How structural plasticity entails transductional adaptability 46
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels 46
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin 46
Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features 46
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors 44
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 42
Pharmacological targeting of neuronal Kv7.2/3 channels: A focus on chemotypes and receptor sites 40
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 39
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 39
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 38
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology 38
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 37
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes 37
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 37
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 37
Comparative Safety of Originator and Biosimilar Epoetin Alfa Drugs: An Observational Prospective Multicenter Study 36
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4- chloro-benzyl)amino]-N-[[(2,4-dimethylbenzyl)-amino]iminomethyl] -pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca 2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 36
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists 36
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy 35
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 34
COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study 33
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP 2 -Dependent K + Channel Gating 33
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 32
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 31
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 30
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 27
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months 24
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine 15
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 13
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes 11
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 8
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy 8
KCNT2-related disorders: phenotypes, functional and pharmacological properties 5
De novo variants in KCNA3 cause developmental and epileptic encephalopathy 3
Totale 2.035
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Categoria #
all - tutte 12.287
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 12.287
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019103 0 0 0 0 0 0 0 0 0 0 5 98
2019/2020389 90 10 27 39 3 77 21 72 1 44 3 2
2020/2021468 43 40 16 44 12 107 2 44 51 53 50 6
2021/2022281 7 8 133 30 0 5 3 48 16 3 3 25
2022/2023558 132 24 3 44 30 106 1 47 107 9 36 19
2023/2024193 38 36 16 9 9 10 10 0 53 12 0 0
Totale 2.035