IRIS
AMBROSINO, Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 1.360
EU - Europa 952
AS - Asia 601
SA - Sud America 189
AF - Africa 18
Continente sconosciuto - Info sul continente non disponibili 14
Totale 3.134
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Nazione #
US - Stati Uniti d'America 1.211
CN - Cina 293
UA - Ucraina 246
FR - Francia 200
BR - Brasile 171
SG - Singapore 171
CA - Canada 138
SE - Svezia 134
IT - Italia 116
DE - Germania 81
FI - Finlandia 49
GB - Regno Unito 45
TR - Turchia 37
NL - Olanda 36
HK - Hong Kong 30
IN - India 18
EU - Europa 14
RU - Federazione Russa 14
AR - Argentina 9
JP - Giappone 9
CI - Costa d'Avorio 7
IQ - Iraq 7
MX - Messico 6
PK - Pakistan 6
CZ - Repubblica Ceca 5
VN - Vietnam 5
AT - Austria 4
IL - Israele 4
MA - Marocco 4
BE - Belgio 3
BO - Bolivia 3
EC - Ecuador 3
KG - Kirghizistan 3
PL - Polonia 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
BD - Bangladesh 2
CH - Svizzera 2
EE - Estonia 2
EG - Egitto 2
IE - Irlanda 2
KZ - Kazakistan 2
LT - Lituania 2
NP - Nepal 2
PA - Panama 2
PT - Portogallo 2
TN - Tunisia 2
UZ - Uzbekistan 2
VE - Venezuela 2
AL - Albania 1
BH - Bahrain 1
DZ - Algeria 1
ES - Italia 1
ET - Etiopia 1
HN - Honduras 1
ID - Indonesia 1
IR - Iran 1
JM - Giamaica 1
JO - Giordania 1
KE - Kenya 1
LU - Lussemburgo 1
LV - Lettonia 1
MT - Malta 1
NI - Nicaragua 1
QA - Qatar 1
RO - Romania 1
TH - Thailandia 1
UY - Uruguay 1
Totale 3.134
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Città #
Jacksonville 203
Toronto 127
Chandler 126
The Dalles 116
Boardman 82
Singapore 68
Strasbourg 48
Helsinki 47
Princeton 45
Wilmington 42
Nanjing 41
Dearborn 29
Hong Kong 29
London 29
Istanbul 27
Meppel 26
Napoli 24
Ogden 21
Shenyang 19
Falkenstein 17
Los Angeles 17
Chicago 16
Guangzhou 16
Milan 15
Shanghai 15
Jinan 14
Ningbo 14
Jiaxing 13
São Paulo 12
Ashburn 11
Beijing 11
Changsha 11
Seattle 11
Zhengzhou 11
Ann Arbor 10
Brooklyn 10
Nanchang 10
Boydton 9
Düsseldorf 9
Tianjin 9
Hebei 8
Abidjan 7
Bremen 7
Santa Clara 7
Amsterdam 6
Assago 6
Belo Horizonte 6
Columbus 6
Frankfurt am Main 6
Munich 6
Norwalk 6
Redwood City 6
Rio de Janeiro 6
Taizhou 6
Xi'an 6
Angri 5
Ankara 5
Atlanta 5
Dallas 5
Hangzhou 5
Mexico City 5
Naples 5
New York 5
Porto Alegre 5
Pune 5
Stockholm 5
Boston 4
Brno 4
Cagliari 4
Chennai 4
Gunzenhausen 4
Ottawa 4
Secaucus 4
Shenzhen 4
Tokyo 4
Bishkek 3
Brussels 3
Buffalo 3
Charlotte 3
Introdacqua 3
La Paz 3
Lauterbourg 3
Montreal 3
North Charleston 3
Orange 3
Pomigliano D'arco 3
Portland 3
Redmond 3
Roubaix 3
Rui'an 3
Saint-maur-des-fossés 3
San Francisco 3
Shijiazhuang 3
Warsaw 3
Wuhan 3
Ancona 2
Baghdad 2
Baku 2
Belford Roxo 2
Benevento 2
Totale 1.666
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Nome #
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 107
Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons 95
Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain 90
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide 86
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 81
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy 78
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 78
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 77
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 77
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 77
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 76
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy 75
Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin 74
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors 73
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 70
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 70
COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study 69
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels 68
Neurounina-1, a novel compound that increases Na+/Ca 2+ exchanger activity, effectively protects against stroke damage 68
The ever changing moods of calmodulin: How structural plasticity entails transductional adaptability 65
Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features 65
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin 63
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia 61
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels 61
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin 61
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes 58
Comparative Safety of Originator and Biosimilar Epoetin Alfa Drugs: An Observational Prospective Multicenter Study 57
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 57
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 53
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 53
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4- chloro-benzyl)amino]-N-[[(2,4-dimethylbenzyl)-amino]iminomethyl] -pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca 2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 53
Pharmacological targeting of neuronal Kv7.2/3 channels: A focus on chemotypes and receptor sites 53
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology 52
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 51
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 51
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 51
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy 51
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine 50
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 49
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 49
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists 49
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes 48
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP 2 -Dependent K + Channel Gating 48
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 48
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months 47
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 46
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 44
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 41
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel 35
KCNT2-related disorders: phenotypes, functional and pharmacological properties 34
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy 33
De novo variants in KCNA3 cause developmental and epileptic encephalopathy 32
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 31
Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study 27
Pharmacological approaches in drug-resistant pediatric epilepsies caused by pathogenic variants in potassium channel genes 14
Totale 3.230
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Categoria #
all - tutte 23.052
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.052
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021425 0 40 16 44 12 107 2 44 51 53 50 6
2021/2022281 7 8 133 30 0 5 3 48 16 3 3 25
2022/2023558 132 24 3 44 30 106 1 47 107 9 36 19
2023/2024238 38 36 16 9 9 10 10 0 53 12 18 27
2024/20251.020 69 15 39 30 99 82 106 82 128 178 123 69
2025/2026130 122 8 0 0 0 0 0 0 0 0 0 0
Totale 3.230