Evidence of Seismic-Related Liquefaction Processes within the Volcanic Record of the Campi Flegrei Caldera (Italy)

We report the occurrence of several sand liquefaction structures, such as sand dikes, in the stratigraphic record of the Campi Flegrei volcano, located both inside and outside the caldera. Five sites were analyzed within the caldera and two outside. The grain size analysis of the sand fillings indicates that these deposits are very fine-to-coarse sands generally poorly sorted. All of the granulometry curves fall within the field of the liquefiable, loose sediments. Frequently, dikes are chara...

Carta geologica della Campania: nota illustrativa sintetica

Bcl-10, trypsin and synaptophysin helps recognize acinar cell and mixed acinar neuroendocrine cell carcinoma of the pancreas on both preoperative cytological samples and needle biopsy specimens

Acinar cell carcinoma (ACC) of the pancreas are known to be rare and difficult to be recognize because they mimic other unrelated tumors (neuroendocrine, solid pseudopapillary) with different clinical behavior. Especially in the setting of inoperable patients, fine needle aspiration cytology (FNAC), core needle biopsy (FNAB) and immunocyto/histochemistry (ICC/IHC) play a crucial role in the differential diagnosis. The biological material available for ICC tests obtained by minimal invasive pr...

Evidence-Based Second-Line Treatment in RAS Wild-Type/Mutated Metastatic Colorectal Cancer in the Precision Medicine Era

Target-oriented agents improve metastatic colorectal cancer (mCRC) survival in combination with chemotherapy. However, the majority of patients experience disease progression after first-line treatment and are eligible for second-line approaches. In such a context, antiangiogenic and anti-Epidermal Growth Factor Receptor (EGFR) agents as well as immune checkpoint inhibitors have been approved as second-line options, and RAS and BRAF mutations and microsatellite status represent the molecular ...