(Chemical Presented). Activated 3-substituted isoindolinones have proved to be efficient nucleophiles in K2CO3-catalyzed Michael reactions of several types of electron-deficient olefins. Moreover, tricyclic pyrrolizidines have been conveniently synthesized via a modification of the described general protocol as a consequence of a cascade Michael/cyclization reaction of unsaturated aldehydes.

3-Carboxylate-Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions

Filosa R.;
2015-01-01

Abstract

(Chemical Presented). Activated 3-substituted isoindolinones have proved to be efficient nucleophiles in K2CO3-catalyzed Michael reactions of several types of electron-deficient olefins. Moreover, tricyclic pyrrolizidines have been conveniently synthesized via a modification of the described general protocol as a consequence of a cascade Michael/cyclization reaction of unsaturated aldehydes.
2015
Conjugated addition
isoindolinones
nitrogen heterocycles
pyrrolizidines
synthetic methods
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12070/45459
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