In this work we report a facile access to a 3,3-disubstituted isobenzofuranone by tandem addition/cyclization reaction to methyl 2-acetylbenzoate in the presence of dimethyl malonate, under basic conditions.

Dimethyl 2-(1-methyl-3-oxo-1,3- dihydroisobenzofuran-1-yl)malonate

Filosa R.
Supervision
;
2020-01-01

Abstract

In this work we report a facile access to a 3,3-disubstituted isobenzofuranone by tandem addition/cyclization reaction to methyl 2-acetylbenzoate in the presence of dimethyl malonate, under basic conditions.
2020
Cascade reactions
Isobenzofuranone
Phthalide
Quaternary carbon
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12070/45403
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