IRIS

Human microsatellite-stable (MSS) colorectal cancers (CRCs) are immunologically "cold" tumour subtypes characterized by reduced immune cytotoxicity. The molecular linkages between immune-resistance and human MSS CRC is not clear.

JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer

CARUSO, Francesca Pia;Cerulo, Luigi;Pancione, Massimo
Conceptualization
2019-01-01

Abstract

Human microsatellite-stable (MSS) colorectal cancers (CRCs) are immunologically "cold" tumour subtypes characterized by reduced immune cytotoxicity. The molecular linkages between immune-resistance and human MSS CRC is not clear.
2019
Colorectal cancer; Immune resistance; LY6G6D; Microsatellite-stable; B7-H1 Antigen; Benzamides; Cell Line, Tumor; Colorectal Neoplasms; DNA Mismatch Repair; Female; Fucosyltransferases; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Janus Kinase 1; Janus Kinase 2; Lewis X Antigen; MAP Kinase Signaling System; Male; Microsatellite Instability; Mitogen-Activated Protein Kinase Kinases; Programmed Cell Death 1 Receptor; Pyrimidines; STAT5 Transcription Factor; T-Lymphocytes
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12070/40446
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